Crude. First Python "App" Ever. Works.
Controls an Asus DUO (loving this Laptop).

 #!/usr/bin/env python3
 import subprocess
 import tkinter as tk
 from tkinter import ttk
 # main window
 root = tk.Tk()
 
 def trackpadon():
     print('Trackpad ON')
     subprocess.run(["xinput","-enable","ASUS Zenbook Duo Keyboard Touchpad"]) 
     subprocess.run(["xinput","-enable","Primax Electronics Ltd. ASUS Zenbook Duo Keyboard Touchpad"])
 
 def trackpadoff():
     print('Trackpad OFF')
     subprocess.run(["xinput","-disable","ASUS Zenbook Duo Keyboard Touchpad"]) 
     subprocess.run(["xinput","-disable","Primax Electronics Ltd. ASUS Zenbook Duo Keyboard Touchpad"])
 
 def screenone():
     print('SCREEN ONE')
     subprocess.run(["xrandr","--output","eDP-1","--auto"])
     subprocess.run(["xrandr","--output", "eDP-2","--off"])
     subprocess.run(["xrandr","--output", "HDMI-1","--off"])
 
 def screentwo():
     print('SCREEN TWO')
     subprocess.run(["xrandr","--output","eDP-2","--auto", "--below", "eDP-1"])
 
 def screenthree():
     print('SCREEN THREE')
     subprocess.run(["xrandr","--output","eDP-1","--auto"])
     subprocess.run(["xrandr","--output","eDP-2","--auto", "--below", "eDP-1"])
     subprocess.run(["xrandr","--output","HDMI-1","--auto", "--above", "eDP-1"])
 
 def screenhdmionly():
     print('HDMI ONly')
     subprocess.run(["xrandr","--output", "eDP-2","--off"])
     subprocess.run(["xrandr","--output", "eDP-1","--off"])
     subprocess.run(["xrandr","--output","HDMI-1","--auto"])
 
 def screenhdmione():
     print('HDMI and Top One')
     subprocess.run(["xrandr","--output", "eDP-2","--off"])
     subprocess.run(["xrandr","--output", "eDP-1","--auto"])
     subprocess.run(["xrandr","--output","HDMI-1","--auto"])
 
 root.geometry('300x500')
 root.resizable(False, False)
 root.title('ASUS Doer')
 
 # exit button
 screen_trackpadon = ttk.Button(
     root,
     text='Trackpad ON',
     command=lambda: trackpadon()
 )
 screen_trackpadoff = ttk.Button(
     root,
     text='Trackpad OFF',
     command=lambda: trackpadoff()
 )
 
 screen_one = ttk.Button(
     root,
     text='ONE screens',
     command=lambda: screenone()
 )
 
 screen_two = ttk.Button(
     root,
     text='TWO screens',
     command=lambda: screentwo()
 )
 
 screen_three = ttk.Button(
     root,
     text='THREE screens',
     command=lambda: screenthree()
 )
 
 screen_hdmionly = ttk.Button(
     root,
     text='HDMI Only',
     command=lambda: screenhdmionly()
 )
 
 screen_hdmione = ttk.Button(
     root,
     text='HDMI and One',
     command=lambda: screenhdmione()
 )
 
 
 # exit button
 exit_button = ttk.Button(
     root,
     text='Exit',
     command=lambda: root.quit()
 )
 
 screen_trackpadon.pack(
     ipadx=5,
     ipady=5,
     expand=True
 )
 screen_trackpadoff.pack(
     ipadx=5,
     ipady=5,
     expand=True
 )
 screen_one.pack(
     ipadx=5,
     ipady=5,
     expand=True
 )
 screen_two.pack(
     ipadx=5,
     ipady=5,
     expand=True
 )
 screen_three.pack(
     ipadx=5,
     ipady=5,
     expand=True
 )
 
 screen_hdmione.pack(
     ipadx=5,
     ipady=5,
     expand=True
 )
 
 screen_hdmionly.pack(
     ipadx=5,
     ipady=5,
     expand=True
 )
 
 exit_button.pack(
     ipadx=5,
     ipady=5,
     expand=True
 )
 root.mainloop()